Reportedly, the cancer patients on immunotherapy cost worse if they have lately taken antibiotics, with their retort and entire survival rate “cracking.” The results were obtained from a research of around 200 cancer patients in the U.K. receiving a type of immunotherapy known as checkpoint inhibitors, which is a part of the regular treatment pathway for cancer sufferers on the NHS (National Health Service). The scientists discovered that patients who received a wide range of antibiotics in the month preceding it to the treatment had considerably worse reactions to immunotherapy. In comparison to patients without and with antibiotics and the immunotherapy, antibiotic treatment prior to immunotherapy was linked with fewer survival rates and patients’ cancer was more prone to develop.
The scientists recommended this might be as antibiotics disturb the balance of microbes and bacteria in the gut (microbiome), which in return affect the immune system. The study was conducted at the ICL (Imperial College London) and was published in the journal JAMA Oncology. The study highlighted the significance of the timing of antibiotic treatment and the requirement for additional studies to understand the mechanism. The study showed that patients with previous antibiotic use had a mean overall survival of 2 Months, in correlation to 26 Months for those with no antibiotic use before treatment.
On a similar note, recently, a study showed that common antibiotics can augment the risk of colon cancer. Though antibiotics could aid in killing the harmful bacteria, the drugs might amplify the risk for cancer, as per to a new report. In recent time, the scientists from JHUSOM (Johns Hopkins University School of Medicine) conducted a study to determine the link amid the use of oral antibiotic and colon cancers. The research was published in the journal Gut and stated that about 70% of patients having rectal and colon cancers were prescribed antibiotics, in comparison to just 68% of those who did not have cancer.